Allergy, Asthma, Immunology of Delaware
Nasheds, PA          Maher Nashed MD

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Vitamin D
People with low vitamin D have more frequent infections than those with normal levels.
Children with history of asthma who took vitamin D experience 6-fold reduction in asthma attacks.
Those with low vitamin D have more allergy marker that others.

The presence of upper respiratory tract infections (URI) in NHANES III was higher with lower [25(OH)D] levels, regardless of season of year. This association was even stronger in subjects with asthma. [Ginde, AA et al. Arch Intern Med. 2009;169:384-390].
Children with a history of asthma who took vit D experienced a 6-fold reduction in asthma attacks [Urashima, M et al. Am J Clin Nutr. 2010;91(5):1255-1260]. Compared with normal vit D levels, those with vit D insufficiency/deficiency had:
– Poorer lung function (FEV₁ & FEV₁/FVC)
– Higher levels of IgE
– More likely need for ICS & OCS
– More likely need for LABA
• Children taking ICS or OCS had lower vit D levels in a doserelated
manner (p = 0.001)

Vitamin D and Frequent
Infections

Vitamin D and Asthma

Children with low Vitamin D
Children with a history of asthma who took vit D experienced a 6-fold reduction in asthma attacks [Urashima, M et al. Am J Clin Nutr. 2010;91(5):1255-1260]. Compared with normal vit D levels, those with vit D insufficiency/deficiency had:
– Poorer lung function (FEV₁ & FEV₁/FVC), Higher levels of IgE, 
– More likely need for ICS & OCS
– More likely need for LABA
• Children taking ICS or OCS had lower vit D levels in a doserelated manner (p = 0.001)

Probiotic and Viral infections

Probiotics (except acidophilus) can decrease the chance of getting viral infections. They also might decrease allergy sensitization and the allergy marker in the body.